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Functional genomic screens with death rate analyses reveal mechanisms of drug action.
Honeywell ME, Isidor MS, Harper NW, Fontana RE, Birdsall GA, Cruz-Gordillo P, Porto SA, Jerome M, Fraser CS, Sarosiek KA, Guertin DA, Spinelli JB, Lee MJ. Honeywell ME, et al. Among authors: porto sa. Nat Chem Biol. 2024 Mar 13. doi: 10.1038/s41589-024-01584-7. Online ahead of print. Nat Chem Biol. 2024. PMID: 38480981
p53 controls choice between apoptotic and non-apoptotic death following DNA damage.
Honeywell ME, Isidor MS, Harper NW, Fontana RE, Cruz-Gordillo P, Porto SA, Fraser CS, Sarosiek KA, Guertin DA, Spinelli JB, Lee MJ. Honeywell ME, et al. Among authors: porto sa. bioRxiv [Preprint]. 2023 May 16:2023.01.17.524444. doi: 10.1101/2023.01.17.524444. bioRxiv. 2023. PMID: 36712034 Free PMC article. Preprint.